The Laboratory of Biochemistry & Structural Biology at the University of Science and Technology of China was established in 2004, formed by the collaboration of two independent research groups led by Professors CongZhao Zhou and Yuxing Chen. The laboratory is affiliated with both the Division of Life Sciences and Medicine and the National Research Center for Physical Sciences at the Microscale. Current members include Associate Professors YongLiang Jiang, WeiFang Li, Xu Li, WenTao Hou, and Qiong Li, as well as Assistant Researcher YanMin Ren, several postdoctoral researchers, approximately 20 doctoral students, over 10 master's students, and several undergraduate students.

With funding from the Chinese Academy of Sciences, the Ministry of Science and Technology, the National Natural Science Foundation, and the Anhui Provincial Department of Science and Technology, the laboratory has entered a stable development phase after two decades of continuous effort. We have established a mature and comprehensive research platform. Our theoretical framework and methodologies encompass (but are not limited to) biochemistry, molecular biology, structural biology, microbiology, bioinformatics, synthetic biology, biophysics, and cell biology, enabling systematic studies of scientific questions of interest at various levels, from atomic/molecular to cellular/individual. Thanks to our collective efforts, a series of results have been published in prestigious journals such as Nature Plants, Nature Structural & Molecular Biology, Nature Cardiovascular Research, Nature Communications, PNAS, Cell Research, and Microbiome.